Search results for "mass [target]"
showing 10 items of 514 documents
A parametric CFD study of hollow fiber membrane modules for hemodialysis
2022
Hemodialysis is a membrane-based process in which solute transport from the patient’s blood to a rinsing solution (dialysate) occurs by diffusion and ultrafiltration. Devices used in hemodialysis are cylindrical modules filled with hollow-fiber membranes which allow the removal of toxic substances and metabolic wastes from the blood, but inhibit the passage of proteins and cells to the dialysate. A predictive porous-media model of hemodialysis was developed and validated against experimental data. Unlike previous literature models, it requires only basic membrane properties (hydraulic and diffusive permeabilities and reflection coefficients) instead of relying on empirically adjusted global…
A porous media CFD model for the simulation of hemodialysis in hollow fiber membrane modules
2022
A computational model was developed to predict the performance of hollow fiber membrane hemodialyzers. Blood and dialysate were modelled as fluids flowing through two interpenetrating porous media. Concerning hydrodynamics, experimental Darcy permeabilities measured for commercial hemodialyzers were used for both compartments. Concerning mass transfer, both diffusion and ultrafiltration were simulated. On the blood side theoretical Sherwood numbers for parallel flow in pipes were adopted. On the dialysate side Sherwood numbers were derived from CFD predictions for regular hexagonal fiber bundles. Solute concentrations on the two sides were alternatively computed in an iterative way and were…
Performance Comparison of Alternative Hollow-Fiber Modules for Hemodialysis by Means of a CFD-Based Model
2022
Commercial hemodialyzers are hollow-fiber cylindrical modules with dimensions and inlet–outlet configurations dictated mostly by practice. However, alternative configurations are possible, and one may ask how they would behave in terms of performance. In principle, it would be possible to depart from the standard counter-flow design, while still keeping high clearance values, thanks to the increase in the shell-side Sherwood number (Sh) due to the cross-flow. To elucidate these aspects, a previously developed computational model was used in which blood and dialysate are treated as flowing through two interpenetrating porous media. Measured Darcy permeabilities and mass transfer coefficients…
Flow and mass transfer in spacer-filled channels for reverse electrodialysis: a CFD parametrical study
2016
Abstract In reverse electrodialysis (RED) concentration polarization phenomena and pressure drop affect strongly the power output obtainable; therefore the channel geometry has a crucial impact on the system optimization. Both overlapped and woven spacers are commonly commercialised and adopted for RED experiments; the latter exhibit some potential advantages, such as better mixing and lower shadow effect, but they have been poorly investigated in the literature so far. In this work, computational fluid dynamics was used to predict fluid flow and mass transfer in spacer-filled channels for RED applications. A parametric analysis for different spacer geometries was carried out: woven (w) and…
CFD study on the influence of water transpiration on flow and mass transfer in channels with bipolar membranes
2018
The future energetic supply based on the massive use of renewable sources poses issues linked to fluctuations of power produced and consumed, thus requiring the use of energy storage systems.
Comparison of different hollow fibre haemodialysis module configurations by a CFD multiscale approach
2021
Objectives The study aims to predict 3-D flow and solute concentrations fields both for blood and dialysate and overall performance parameters (such as dialysate pressure drop and clearance) for different hollow-fibre haemodialysis modules. Methods A multiscale approach was used. At small (unit cell)-scale, dialysate flow and mass transfer around straight cylindrical fibres arranged in regular lattices were simulated. At module-scale, hydraulic permeabilities and mass transfer coefficients derived from small-scale simulations were used to define two different porous media representative of blood and dialysate, sharing the same volume and exchanging solute. Simulations involved different mod…
CFD Simulation of Mass Transfer Phenomena in Spacer Filled Channels for Reverse Electrodialysis Applications
2013
Salinity Gradient Power via Reverse Electrodialysis is a topic of primary importance nowadays. It allows getting energy from the “controlled” mixing of solutions at different salt concentration. The performance of this technology depends on many factors such as: components properties (i.e. membranes, spacers, electrodes), stack geometry, operating conditions and feeds features. Concentration polarization phenomena may significantly affect the actual membrane potential, thus reducing the gross power produced. On the other hand, C-polarization phenomena may significantly be reduced by suitably choosing the hydrodynamic regime within the stack. Such a choice may in turn significantly require h…
Oxygen Transfer Performances of Unbaffled Bio_Reactors with Various Aspect Ratios
2014
Cultivation of microorganisms, plants or animal cells requires liquid agitation in order to ensure oxygen and nutrient transfer and to maintain cell suspension. Many studies on animal cell damage due to mechanical agitation and sparging aeration have shown that mechanical damage of freely suspended animal cells is in most cases associated with bursting bubbles at the air–liquid interface (Barrett et al., 2010). Gas bubbles are usually generated by direct air sparging aimed at supplying oxygen to the culture medium. Mechanical agitation may also introduce gas bubbles in the culture medium via vortexing entrainment from the free surface. In this work oxygen transfer performance of an unbaffle…
Numerical Simulations of a Flux Rope Ejection
2015
Coronal mass ejections (CMEs) are the most violent phenomena observed on the Sun. One of the most successful models to explain CMEs is the flux rope ejection model, where a magnetic flux rope is expelled from the solar corona after a long phase along which the flux rope stays in equilibrium while magnetic energy is being accumulated. However, still many questions are outstanding on the detailed mechanism of the ejection and observations continuously provide new data to interpret and put in the context. Currently, extreme ultraviolet (EUV) images from the Atmospheric Imaging Assembly (AIA) on board the Solar Dynamic Observatory (SDO) are providing new insights into the early phase of CME evo…
A prospective new diagnostic technique for distinguishing eruptive and noneruptive active regions
2019
This research has received funding from the Science and Technology Facilities Council (UK) through the consolidated grant ST/N000609/1 and the European Research Council (ERC) under the European Union Horizon 2020 research and innovation program (grant agreement No. 647214). This work used the DiRAC@Durham facility managed by the Institute for Computational Cosmology on behalf of the STFC DiRAC HPC Facility (www.dirac.ac.uk). The equipment was funded by BEIS capital funding via STFC capital grants ST/P002293/1, ST/R002371/1, and ST/S002502/1, Durham University and STFC operations grant ST/R000832/1. DiRAC is part of the National e-Infrastructure. S.L.Y. would like to acknowledge STFC for sup…